NATASCIA TISO
Title: Professore associato
SSD: BIO/13 - Applied Biology
Address: VIALE GIUSEPPE COLOMBO, 3 - VIA UGO BASSI, 58/B - PADOVA
Phone: 0498276302
E-mail: natascia.tiso@unipd.it
Teaching in current academic year
Course | Degree |
---|---|
MODEL ORGANISMS IN BIOLOGICAL RESEARCH |
Curriculum
PUBLICATIONS: 102 publications; 5655 citations; 55 cit/article; h-index=33 (Google Scholar: h-index=38) >100 international and >50 national presentations TITLES AND WORK EXPERIENCES 1994: Degree in Biological Sciences, Biomolecular Course, 110/110 cum laude 1996: Official State Exam as Professional Biologist 1997: Visiting Scientist at the University of Toronto, Ontario, Canada 1998: PhD in Genetic Sciences, Univ. of Bologna, Ferrara and Padua 1999-2000: Post-doctorate in Genetics of Hereditary Cardiomyopathies, Univ. Padua 2001-2007: EU Research Collaborator - Model organism: zebrafish (Danio rerio) 2005: Stage at MPI Tuebingen, Germany, Lab. of Nobel Prize Prof. C.N. Volhard 2007-2015: University Researcher, Dept. of Biology, UniPD 2015-present: Associate Professor, Dept. of Biology, UniPD AWARDS AND SCHOLARSHIPS 1997: Telethon annual scholarship for training abroad 1997: "Lions Club Verona Europa" award for arrhythmogenic cardiomyopathy 2001: "Martino Arrigoni" Award for Congenital Cardiopathies, Rotary Club BL 2003: "Alberto Monroy" Award for the MBL course, USA, University of Palermo 2003: L'Oreal-UNESCO Award (on ARVD) for Women and Science in Italy 2003: Howard Hughes Medical Institute Award (MBL Embryology Course 2003) USA 2008-present: Annual Mobility Fellowship Winner, Univ. Padova / Univ. Freiburg Exchange 2013: Poster Prize COB, European Zebrafish Meeting, Barcelona, Spain 2017: Poster Prize EASD-ISG / BCW, 2nd EASD-ISG / BCW Joint Meeting, Dresden, Germany FUNDING 2002-2003: Young Researcher Funding on: ARVD, UniPD 2004: EU Research Collaborator II Level, Co-PI EU Project ZF-MODELS 2008: Curator of the Didactic Fund Project (40,000 Euros), UniPD 2009: PI - University Project (on: Alagille Syndrome). Euro 60,000, UniPD 2009-present: holder of DOR funds - Ministry of Education, University and Research 2009: Curator of the Didactic Fund Project (40,000 Euros), UniPD 2009: "Large Equipment" Project Curator (Euro 220,000), UniPD 2011: Visiting Scientist Project winner (Euro 5000), UniPD 2011: Curator of the Didactic Fund Project (86,000 Euros), UniPD 2012: PI Unit, Finalized Research Proj. (on: CH) (Euro 59.124),UniMI 2013: Junior Post-doc Biennial Fellowship (on CH), (25,000x2 Euros) 2013: Co-PI University Proj. "Optozen" (Euro 8,000) (on: Imaging in ZF), UniPD 2014: Co-PI University Proj. "TIGRE" (55,000 euros), UniPD 2015: PI in the project "POLYGON" (50,000 euros), AFM-Telethon, France 2018: Unit Pi, project "SHoCD" (350,000 euros), Cariparo Foundation, Padova, Italy 2019: CoPI in the Italian Telethon Project "ZIPPY" GGP19287 (Euro 188.100), Italy TEACHING AND ACADEMIC ACTIVITIES 2007-2011: holder of the course "Molecular Biology of Development, Mod. B", Sc. Sciences, UniPD 2011-present: holder of the course "Model Organisms in Biology", School of Sciences, UniPD 2015-present: holder of the courses "Applied Biology" and "Genetics", School of Psychology, UniPD Associations: AGI (Italian Genetic Association), European Zebrafish Society, Science Advisory and Healthcare Advisory Board, GSA (Genetics Society of America), ASBMB, SBMR, European Society for Fish Models in Biology and Medicine Reviewer for about 20 international journals with IF and peer review WEB SITES: ZFIN: http://zfin.org/cgi-bin/webdriver?MIval=aa-persview.apg&OID=ZDB-PERS-020116-8 ResearchGate: https://www.researchgate.net/profile/Natascia_Tiso/
Curriculum in PDF: English CV
Articles published in the last 5 years
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An adaptive registration algorithm for zebrafish larval brain images.
COMPUT METH PROG BIO2022Deb S, Tiso N, Grisan E, Chowdhury AS -
Biodegradable nanoparticles combining cancer cell targeting and anti‑angiogenic activity for synergistic chemotherapy in epithelial cancer.
DRUG DELIV TRANSL RE2022Francesca Moret, Claudia Conte, Diletta Esposito, Giovanni Dal Poggetto, Concetta Avitabile, Francesca Ungaro, Natascia Tiso, Alessandra Romanelli, Paola Laurienzo, Elena Reddi, Fabiana Quaglia -
Fast whole-brain imaging of seizures in zebrafish larvae by two-photon light-sheet microscopy
BIOMED OPT EXPRESS2022G de Vito, L Turrini, C Müllenbroich, P Ricci, G Sancataldo, G Mazzamuto, N Tiso, L Sacconi, D Fanelli, L Silvestri, F Vanzi, FS Pavone -
Hyperactivation of Wnt/ β-catenin and Jak/ Stat3 pathways in human and zebrafish foetal growth restriction models: Implications for pharmacological rescue
FRONT CELL DEV BIOL2022Risato G., Celeghin R., Brañas Casas R., Dinarello A., Zuppardo A., Vettori A., Pilichou K., Thiene G., Basso C., Argenton F., Visentin S., Cosmi E., Tiso N., Beffagna G. -
Macrophage-Mediated Melanoma Reduction after HP-NAP Treatment in a Zebrafish Xenograft Model.
INT J MOL SCI2022Codolo G, Facchinello N, Papa N, Bertocco A, Coletta S, Benna C, Dall'Olmo L, Mocellin S, Tiso N, de Bernard M
Research area
Research Areas: Human Genetics, Genetics - Developmental Dynamics and Molecular Biology, Zebrafish (Danio rerio) and Human Pathology. Research lines: a) Use of zebrafish as a model for human arrhythmogenic cardiomyopathy b) Use of zebrafish as a model for human mitochondrial disorders c) Use of zebrafish as a model for the FGR human condition d) Use of zebrafish for in vivo analysis of cell signaling e) Use of zebrafish for the analysis and treatment of human cancer cells. Techniques: production and analysis of transgenic zebrafish lines, biosensors and mutants; classical and confocal microscopy; microinjection of constructs, mRNA and morpholino oligos into zebrafish zygotes; xeno-transplantation of human tumor cells; immunohistochemistry and in situ hybridization on whole embryo; routine techniques in genetics and molecular biology; gene targeting via CRISPR-Cas9 technology.
Proposals for thesis
Master's thesis topics: a) Use of zebrafish as a model for human arrhythmogenic cardiomyopathy b) Use of zebrafish as a model for human mitochondrial disorders c) Use of zebrafish as a model for the FGR human condition d) Use of zebrafish for in vivo analysis of cell signaling e) Use of zebrafish for the analysis and treatment of human cancer cells. Bachelor's thesis; activities and techniques on display: a) Practical activities for laboratory management (cleaning of work areas, sterilization of materials, instrumentation calibration and maintenance) b) Basic techniques in molecular biology (nucleic acid extraction, PCR and genotyping, gel electrophoresis) c) Embryological techniques on the zebrafish model (collection and manipulation of fertilized eggs, observation of developmental stages, fixation, immuno-histochemistry and in situ hybridization, in vivo and post-mortem observations and documentation by classical bright-field/fluorescence and confocal optical microscopy.