

VANESSA CHECCHETTO
Title: Ricercatore a tempo determinato di tipo A
SSD: BIO/10 - Biochemistry
Address: VIA U. BASSI, 58/B - PADOVA
Phone: 0498276336
E-mail: vanessa.checchetto@unipd.it
Teaching in current academic year
Curriculum
Curriculum in PDF: English CV
Research area
From 2010 to 2021 I published 34 peer-reviewed papers, several of them in high-impact journals, e.g., Nature, Science, PNAS, Molecular Cell, and main author and 3 in international books. Among these publications, in 14 articles I am first or co-first author, in 1 article I am co-last author and in 5 articles I am corresponding author. In 28 articles I am an author without my Ph.D. supervisor as co-author. Also, I am the author or co-author of 4 conference papers and 1 abstract in conference proceedings. My main contribution to the field of ion channels concerns the discovery/characterization of 3 mitochondrial ion channels with a proven high impact on cancer cell behavior (MCU, VDACs and PTP). I contributed to our understanding of the regulation of the mitochondrial calcium uniporter (MCU) and gave a crucial contribution to the characterization of VDAC3 and the discovery that it acts as a redox sensor in the intermembrane space of mitochondria. I furthermore participated in the studies to identify the molecular components of the permeability transition pore (PTP). Finally, I identified the molecular components of the mitochondrial ATP-dependent potassium channel, important for cardioprotection. I became exposed to research on cancer and now I am willing to comprehend how cancer-related ion channels can be regulated by interaction partners.
Proposals for thesis