

MARINA DE BERNARD
Title: Professore ordinario
SSD: MED/04 - General Pathology
Address: VIA U. BASSI, 58/B - PADOVA
Phone: 0498276309
E-mail: marina.debernard@unipd.it
Teaching in current academic year
Course | Degree |
---|---|
PATHOLOGY AND HISTOPATHOLOGY | Health Biology |
MOLECULAR PATHOLOGY | Sanitary Biology |
Curriculum
Curriculum in PDF: English CV
Articles published in the last 5 years
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Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA
FRONTIERS IN IMMUNOLOGY2020Codolo G, Toffoletto M, Chemello F, Coletta S, Teixidor G, Battaggia G, Munari G, Fassan M, Cagnin S, De Bernard M -
The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation
SCI REP-UK2020Coletta S, Salvi V, Della Bella C, Bertocco A, Lonardi S, Trevellin E, Fassan M, D'Elios MM, Vermi W, Vettor R, Cagnin S, Sozzani S, Codolo G, de Bernard M -
Simulating Inflammation in a Wound Microenvironment Using a Dermal Wound-on-a-Chip Model
ADVANCED HEALTHCARE MATERIALS2019Biglari S, Le TYL, Tan RP, Wise SG, Zambon A, Codolo G, De Bernard M, Warkiani M, Schindeler A, Naficy S, Valtchev P, Khademhosseini A, Dehghani F -
Supercritical carbon dioxide combined with high power ultrasound as innovate drying process for chicken breast
J SUPERCRIT FLUID2019Morbiato G, Zambon A, Toffoletto M, Poloniato G, Dall'Acqua S, de Bernard M, Spilimbergo S -
The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling
CELLULAR MICROBIOLOGY2019Capitani N, Codolo G, Vallese F, Minervini G, Grassi A, Cianchi F, Troilo A, Fischer W, Zanotti G, Baldari CT, De Bernard M, D'Elios MM
Research area
The research interest of our group is the characterization of bacterial factors able to modulate the activity of immune cells, with the aim of defining the immune-based mechanisms responsible for the long-term survival of bacteria responsible for chronic disorders (i.e., Helicobacter pylori). By taking advantage of these bacterial products, the research group has also the ambitious aim of contributing to the knowledge of the physiological mechanisms that modulate the signaling pathways in immune cells.
Proposals for thesis
The research proposals for thesis projects have as a common topic the characterization of the immune modulating properties of bacterial factors produced by pathogens responsible for chronic diseases, in particular Helicobacter pylori. The most interesting factors will be used as tools to contribute to the knowledge of the physiological mechanisms that modulate the signaling pathways in immune cells. During the thesis work the student will have the opportunity to learn: H. pylori culture, isolation of immune cells from human blood, infection and transfection of macrophages, protein ubiquitination assay, immunoprecipitation, SDS-PAGE and western blot, immunofluorescence, qRT-PCR, flow cytometry, ELISA, antigen presentation assay.