Immagine di MARINA DE BERNARD

MARINA DE BERNARD

Title: Professore ordinario

SSD: MED/04 - General Pathology

Address: VIA U. BASSI, 58/B - PADOVA

Phone: 0498276309

E-mail: marina.debernard@unipd.it

Teaching in current academic year

Course Degree
PATHOLOGY AND HISTOPATHOLOGYHealth Biology
MOLECULAR PATHOLOGYSanitary Biology

Curriculum

Curriculum in PDF: English CV

Articles published in the last 5 years

  • Helicobacter pylori Dampens HLA-II Expression on Macrophages via the Up-Regulation of miRNAs Targeting CIITA
    FRONTIERS IN IMMUNOLOGY
    2020
    Codolo G, Toffoletto M, Chemello F, Coletta S, Teixidor G, Battaggia G, Munari G, Fassan M, Cagnin S, De Bernard M
  • The immune receptor CD300e negatively regulates T cell activation by impairing the STAT1-dependent antigen presentation
    SCI REP-UK
    2020
    Coletta S, Salvi V, Della Bella C, Bertocco A, Lonardi S, Trevellin E, Fassan M, D'Elios MM, Vermi W, Vettor R, Cagnin S, Sozzani S, Codolo G, de Bernard M
  • Simulating Inflammation in a Wound Microenvironment Using a Dermal Wound-on-a-Chip Model
    ADVANCED HEALTHCARE MATERIALS
    2019
    Biglari S, Le TYL, Tan RP, Wise SG, Zambon A, Codolo G, De Bernard M, Warkiani M, Schindeler A, Naficy S, Valtchev P, Khademhosseini A, Dehghani F
  • Supercritical carbon dioxide combined with high power ultrasound as innovate drying process for chicken breast
    J SUPERCRIT FLUID
    2019
    Morbiato G, Zambon A, Toffoletto M, Poloniato G, Dall'Acqua S, de Bernard M, Spilimbergo S
  • The lipoprotein HP1454 of Helicobacter pylori regulates T-cell response by shaping T-cell receptor signalling
    CELLULAR MICROBIOLOGY
    2019
    Capitani N, Codolo G, Vallese F, Minervini G, Grassi A, Cianchi F, Troilo A, Fischer W, Zanotti G, Baldari CT, De Bernard M, D'Elios MM




Research area

The research interest of our group is the characterization of bacterial factors able to modulate the activity of immune cells, with the aim of defining the immune-based mechanisms responsible for the long-term survival of bacteria responsible for chronic disorders (i.e., Helicobacter pylori). By taking advantage of these bacterial products, the research group has also the ambitious aim of contributing to the knowledge of the physiological mechanisms that modulate the signaling pathways in immune cells.

Proposals for thesis

The research proposals for thesis projects have as a common topic the characterization of the immune modulating properties of bacterial factors produced by pathogens responsible for chronic diseases, in particular Helicobacter pylori. The most interesting factors will be used as tools to contribute to the knowledge of the physiological mechanisms that modulate the signaling pathways in immune cells. During the thesis work the student will have the opportunity to learn: H. pylori culture, isolation of immune cells from human blood, infection and transfection of macrophages, protein ubiquitination assay, immunoprecipitation, SDS-PAGE and western blot, immunofluorescence, qRT-PCR, flow cytometry, ELISA, antigen presentation assay.