Immagine di LAURA CIVIERO

LAURA CIVIERO

Title: Ricercatore a tempo determinato di tipo B

SSD: BIO/09 - Physiology

Address: VIALE GIUSEPPE COLOMBO, 3 - VIA UGO BASSI, 58/B - PADOVA

Phone: 0498276233

E-mail: laura.civiero@unipd.it

Teaching in current academic year

Curriculum

In 2017, Laura Civiero has been employed as assistant Professor of Physiology at the Department of Biology (UNIPD) and she is now on the tenure-track process to professorship. Since 2010, her work has been based on the identification of targetable processes in Parkinson’s disease. Her most recent studies are focused on the contribution of glial cells to neurodegeneration. So far, she has published 34 papers with 1599 citations and h-index 21 (Google Scholar). During her postdoctoral studies, she has been awarded two short-term EMBO fellowships, one grant as PI to support her salary (UNIPD) and one grant to fund her research as co-PI (MJFF). Her research is currently supported by national (MHO) and intramural (UNIPD) grants. She leads a research team composed by two post-doctoral fellows, one PhD student and three undergraduate students. At her institution, she serves as a PhD Committee member and she is part of the Communications committee. During the last 5 years, she has organised three symposia on the topics of her research at National and International congresses. She is also very active on promoting science to the civil society by participating to multiple dissemination activities.

Curriculum in PDF: English CV

Articles published in the last 5 years

  • Co-occurring WARS2 and CHRNA6 Mutations in a Child With a Severe Form of Infantile Parkinsonism
    PARKINSONISM \& RELATED DISORDERS
    2020
    Martinelli S, Cordeddu V, Galosi S, Lanzo A, Palma E, Pannone L, Ciolfi A, Di Nottia M, Rizza T, Bocchinfuso G, Traversa A, Caputo V, Farrotti A, Carducci C, Bernardini L, Cogo S, Paglione M, Venditti M, Bentivoglio A, Ng J, Kurian MA, Civiero L, Greggio E, Stella L, Trettel F, Sciaccaluga M, Roseti C, Carrozzo R, Fucile S, Limatola C, Di Schiavi E, Tartaglia M, Leuzzi V
  • Ceramides in Parkinson’s Disease: From Recent Evidence to New Hypotheses
    FRONT NEUROSCI-SWITZ
    2019
    Plotegher N, Bubacco L, Greggio E, Civiero L
  • Glial phagocytic clearance in Parkinson's disease
    MOLECULAR NEURODEGENERATION
    2019
    Tremblay M, Cookson MR, Civiero L
  • RAB8, RAB10 and RILPL1 Contribute to Both LRRK2 Kinase-Mediated Centrosomal Cohesion and Ciliogenesis Deficits
    HUM MOL GENET
    2019
    Lara Ordónez AJ, Fernández B, Fdez E, Romo-Lozano M, Madero-Pérez J, Lobbestael E, Baekelandt V, Aiastui A, López de Munaín A, Melrose HL, Civiero L, Hilfiker S
  • PAKs in the brain: Function and dysfunction
    BBA-GEN SUBJECTS
    2018
    Civiero L, Greggio E




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Research area

The brain is a network of neuronal connections surrounded by a scaffold of glial cells with a multitude of crucial functions. A specific type of glial cells, astrocytes, are emerging as modulating factors in diverse brain diseases. Civiero studies how astrocytes contribute to the removal of unwanted and neurotoxic molecules in an effort to maintain brain homeostasis. Her discoveries will help manipulating this function for therapeutic purposes. She is employing a plethora of in vitro, ex vivo and in vivo approaches to unravel the molecular mechanisms behind astrocyte dysfunction and to screen drugs in a high throughput fashion.

Proposals for thesis

Project 1: Identification of glia biomarkers in brain diseases; Project 2: Unraveling the molecular mechanisms of glia-mediated phagocytic clearance; Project 3: Targeting glia reactivity in a model of neurodegeneration