Education and training 2001 Degree in Chemistry, University of Padova with 110/110 and laude 2002 Italian Crystallography Asociation SCUOLA AIC 2002 "Il problema della fase in Cristallografia" (Bressanone,Italy) 2003 Attended European specialized course HERCULES 2003 "Higher European Research Course for Users of Large Experimental Systems" Session B: neutron and synchrotron radiation for biomolecu- lar structure and dynamics (Grenoble, France). 2004 37th Int.School of Crystallography 2005 "Evolving methods for Macromol Crystallography." (E. Majorana center, Erice, Italy) 2005 Ph.D. in Chemistry - Univ. Padova, Italy; PhD thesis subject: “" Structural studies on Cag proteins from the Pathogenicity island of H. pylori." 2005 “European Workshop on Challenging proteins." (Paris, France) 2010 Practical Workshop: “Use of longer wavelengths in Structural Biology.” (Grenoble, France) 2017 Bridging the gap between cryo-EM and crystallography". Pavia, Italy Research activities 2000-2001: Undergraduate student at the Dept. of Organic Chemistry - University of Padova, Italy 2002-2005: Ph.D. student - Department of Chemistry, University of Padova and VIMM Institute. 2005-2009: 4 years Post-graduate fellow at the Dept. of Chemical Sciences of the Univ. of Padova. Field of Study: “Structural Proteomic of Helicobacter pylori pathogenicity island cag-PAI.” 2009-2010: Post-graduate fellow at the Dept. of Biological Chemistry (Padova) Field of Study: “Structural characterization of virulence factors of the bacterium H. pylori.” 2010-2011: Post-graduate fellow at the Dept of Biological Chemistry (University of Padova); “Calcium signaling in health and disease.” 2011-2012: Young Researchers Post-graduate Fellow (“Bando Giovani Studiosi 2011”, University of Padova); “Mapping the maturation cycle of the [fefe]-hydrogenases." 05/2012: Assistant professor - Dept. of Biology (University of Padova, Biochemistry Unit) 54 Scientific publications on peer-reviewed international journals in PubMed ChemMedChem.; ACS Med Chem Lett.; Phytomedicine; Sci. Rep.; J. Biol., Chem.; J. Mol. Biol.; Appl Microbiol Biotechnol.; Plant Cell; Nature Chem. Biol.; J Struct Biol.; Structure; Mol. Micro- biol.; ACS Chem. Biol.; FEBS Lett and FEBS J.; Proteins; Biochemistry; World J Gastroenterol.; Plos One; Biochim Biophys Acta; J. Virol.; Acta Crystallogr. Sect. F; Acta Crystallogr. Sect. D; Int. J. Biochem. Cell. Biol.; IUBMB Life; Mol Pharmacol.; Chembiochem. 4 book chapters contributions (Springer, Pan Stanford Publishing) Bibliometrics The H-INDEX of Laura Cendron is 23 (Google Scholar), 20 (Scopus). Total citations of his manu- scripts are >1270 (Google Scholar)and >910 (Scopus). Research activities in her Lab have been supported by: Italian Ministry of Education; Padova University; Micheal J.Fox Foundation; IIT ( Istituto Italiano di Technologia) Awards/Fellowships 2011 Selected as Young Investigator (“Bando Giovani Studiosi 2011”, University of Padova) 2013 Premio Nardelli for Young Italian Crystallographers who achieved or developed (AIC associa- tion) Membership 2013- Member of the school board of PhD program in Bioscience of the University of Padova. 2016- member of “Commissione didattica” for Bachelor and Master degree in Molecular Biology. Member of the AIC society, Italian partner of IUCr, and SIB society, Italian partner of FEBS.

CARATTERIZZAZIONE STRUTTURALE E FUNZIONALE DI PROTEINE COINVOLTE NEL CONTROLLO DEI FLUSSI DI CALCIO NEI CLOROPLASTI. IL PROGETTO E' SVOLTO IN COLLABORAZIONE CON I GRUPPi DI RICERCA DI DR. LORELLA NAVAZIO E PROF. ILDIKO SZABO'. CARATTERIZZAZIONE STRUTTURALE E FUNZIONALE DI PROTEINE CHE CONFERISCONO RESISTENZA A NUMEROSI CEPPI BATTERICI GRAM-NEGATIVI. IN PARTICOLARE, IL PROGETTO PREVEDE LO STUDIO DI COMPLESSI ENZIMA-INIBITORE DI SVARIATE BETA-LATTAMASI IN COMPLESSO CON COMPOSTI SELEZIONATI MEDIANTE SCREENING IN SILICO E VALIDATI IN VITRO ED E' FINALIZZATO A DESCRIVERE LA MODALITA' DI LEGAME E STABILIRE QUALI SIANO LE INTERAZIONI CHIAVE NELL'INIBIZIONE ESERCITATA DA TALI COMPOSTI. IN PARALLELO UNA NUOVA E PIU' AMPLIA LINEA D'AZIONE VERTE SULLO SVILUPPO DI COMPOSTI IN GRADO DI INIBIRE LA RISPOSTA SOS NEI BATTERI E CONTRASTARE IN QUESTO MODO PIU' IN GENERALE I MECCANISMI DI RESISTENZA BATTERICA. CARATTERIZZAZIONE STRUTTURALE DI ENZIMI DI INTERESSE IN AMBITO BIOTECNOLOGICO. IN PARTICOLARE SARA' DATO AMPIO RILIEVO ALLA CARATTERIZZAZIONE DI ENZIMI CON ATTIVITA' TIPO ENE-REDUTTASI, FMN DIPENDENTI. IL PROGETTO E' SVOLTO IN COLLABORAZIONE CON IL GRUPPO DI RICERCA DELLA PROF. E. BERGANTINO. CARATTERIZZAZIONE DI PROTEINE COINVOLTE NELLA VEICOLAZIONE DI FARMACI E DI COMPLESSI PROTEINA BERSAGLIO -FARMACO. IL PROGETTO E' SVOLTO IN COLLABORAZIONE CON IL GRUPPO DI RICERCA DEL DR. A. ANGELINI.

The Structural Biology Laboratory offers the chance to undergraduate students to be involved in one of the following research themes: 1. Production and characterization of beta-lactamases enzymes for testing new potential classes of inhibitors, in the contest of a project aimed to contrasting Antimicrobials Resistance (AMR). 2. Characterization of the molecular and structural determinants of SOS-response in bacteria: a state-of-the-art approach based on key states trapping and description by high-affinity nanobodies 3. Characterization of the structure, stability and specificity of Enzymes for Biotechnological applications (in collaboration with E. bergantino) 4. Characterization and improvement of drug-carrier complexes and development of new tools for drugs delivery (in collaboration with A. Angelini in Venice and C. Heinis in Lausanne). Students from Molecular Biology, Biotechnology, Biology and Chemistry fields are eligible for an internship in the Structural Biology laboratory.