Curriculum in PDF: English CV

G. CODOLO is interested in elucidating the MOLECULAR PATHWAYS that regulate the innate IMMUNE RESPONSE both in CANCER and in CHRONIC INFECTIONS. In particular, her research is focused on the study of the immune escape mechanisms in cancer and chronic infection.

Our research group is interested in studying the immune evasion mechanisms in tumor context. In particular, we are focused in investigating: - the mechanisms that lead to antigen presentation impairment in colorectal cancer, and mechanisms and pathways leading to intratumoral recruitment of macrophages with anti-inflammatory profile promoting tumor growth. - the relationship between intestinal epithelium and immune system. To this aim, we work mainly with in vivo model of colon cancer and with ex vivo model of intestinal organoids/immune cells co-culture. We adopt combined approaches of cell biology, biochemistry and molecular biology. Interested students can contact me for more informations.